Granulosa cell tumours (GCT) are uncommon stromal ovarian tumours that make up between 5 and 10% of all ovarian cancers. They are hormonally active tumours that can develop at any age, with the fifth and sixth decades seeing the highest occurrence. Granulosa cell tumours are categorised as low-grade malignant neoplasms with a 55–97% 5-year survival rate . However, distant metastases and late recurrences have already been documented. We describe a recurrent GCT with hepatic invasion that appeared on MR imaging 15 years after the first diagnosis.

The reproductive potential of young women with cancer after treatment is a significant issue. Different systems govern how chemotherapy medicines work in the ovaries. The primary mechanism of chemotherapy-induced apoptosis in primordial follicle oocytes was identified as being the cause of the ovarian reserve's irreversible reduction. The DNA damage repair route mediated by ataxia-telangiectasia mutant is the initial pathway used by the oocyte to attempt to repair DNA damage. Apoptosis, or cell death, happens in cells that cannot repair DNA damage.